When is it better to use Vanilla.js instead of React.js?

Using Vanilla.js instead of React.js is better for simple projects where you don’t need advanced features. Vanilla.js has no dependencies, so setup is fast and programs have smaller file sizes, loading quicker. It’s great when all you need is basic interactivity, and it helps improve skills in JavaScript basics and browser DOM work. For simple or performance-focused sites, Vanilla.js can be more effective than React.js.